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1

Metabolism-dependent hepatotoxicity of methimazole in mice depleted of glutathione

Tamio Mizutani, Mihoko Murakami, Mutsuko Shirai, Maki Tanaka, Kazuo Nakanishi

Journal:

Journal of Applied Toxicology

Year:

1999

Language:

english

File:

PDF, 308 KB

english, 1999

2

Observation of the flame structures emerging at low Damköhler number fields

Manabu Fuchihata, Masashi Katsuki, Yukio Mizutani, Tamio Ida

Journal:

Proceedings of the Combustion Institute

Year:

2007

Language:

english

File:

PDF, 693 KB

english, 2007

3

Sulfur-containing metabolites of chlorobiphenyl isomers, a comparative study

Mizutani, Tamio, Yamamoto, Kenji, Tajima, Kazuo

Journal:

Journal of Agricultural and Food Chemistry

Year:

1978

Language:

english

File:

PDF, 693 KB

english, 1978

4

p-Dichlorobenzene-induced hepatotoxicity in mice depleted of glutathione by treatment with buthionine sulfoximine

Tamio Mizutani, Yoshiko Nakahori, Kei-ichi Yamamoto

Journal:

Year:

1994

Language:

english

File:

PDF, 591 KB

english, 1994

5

Derivatization of butylated hydroxytoluene for gas chromatography with electron-capture detection and high-performance liquid chromatography with ultraviolet detection

Tamio Mizutani, Kazuo Tajima, Naoko Okino, Kenji Yamamoto

Journal:

Journal of Chromatography A

Year:

1985

File:

PDF, 160 KB

1985

6

Direct evidence for in vivo hydroxyl radical generation in blood of mice after acute chromium (VI) intake

Yasuji Hojo, Ayako Okado, Sadahiro Kawazoe, Tamio Mizutani

Journal:

Biological Trace Element Research

Year:

2000

Language:

english

File:

PDF, 107 KB

english, 2000

7

In vivo singlet-oxygen generation in blood of chromium(VI)-treated mice

Yasuji Hojo, Ayako Okado, Sadahiro Kawazoe, Tamio Mizutani

Journal:

Biological Trace Element Research

Year:

2000

Language:

english

File:

PDF, 102 KB

english, 2000

8

Uptake of 4-chlorobiphenyl and 4,4′-dichlorobiphenyl in six species of plant tissue cultures

Kenji Yamamoto, Hisako Yamamoto, Tamio Mizutani

Journal:

Bulletin of Environmental Contamination and Toxicology

Year:

1982

Language:

english

File:

PDF, 202 KB

english, 1982

9

Detection of 4-hydroxy-BHT residues in laboratory animals as an indicator of exposure to butylated hydroxytoluene (BHT)

Kenji Yamamoto, Kazuo Tajima, Tamio Mizutani

Journal:

Bulletin of Environmental Contamination and Toxicology

Year:

1984

Language:

english

File:

PDF, 227 KB

english, 1984

10

A comparative study on accumulation and elimination of tetrachlorobiphenyl isomers in mice

Tamio Mizutani, K. Hidaka, T. Ohe, M. Matsumoto

Journal:

Bulletin of Environmental Contamination and Toxicology

Year:

1977

Language:

english

File:

PDF, 374 KB

english, 1977

11

Comparative study on accumulation and elimination of hexachlorobiphenyls and decachlorobiphenyl in mice

Tamio Mizutani, Kimio Hidaka, Takeshi Ohe, Masayoshi Matsumoto, Kenji Yamamoto, Kazuo Tajima

Journal:

Bulletin of Environmental Contamination and Toxicology

Year:

1980

Language:

english

File:

PDF, 218 KB

english, 1980

12

Pulmonary toxicity of butylated hydroxytoluene and related alkylphenols: Structural requirements for toxic potency in mice

Tamio Mizutani, Ichiko Ishida, Kenji Yamamoto, Kazuo Tajima

Journal:

Toxicology and Applied Pharmacology

Year:

1982

Language:

english

File:

PDF, 728 KB

english, 1982

13

Isotope effects on the metabolism and pulmonary toxicity of butylated hydroxytoluene in mice by deuteration of the 4-methyl group

Tamio Mizutani, Kenji Yamamoto, Kazuo Tajima

Journal:

Toxicology and Applied Pharmacology

Year:

1983

Language:

english

File:

PDF, 619 KB

english, 1983

14

Hepatotoxicity of butylated hydroxytoluene and its analogs in mice depleted of hepatic glutathione

Tamio Mizutani, Haruko Nomura, Kazuo Nakanishi, Setsuya Fujita

Journal:

Toxicology and Applied Pharmacology

Year:

1987

Language:

english

File:

PDF, 2.41 MB

english, 1987

15

Oxidative DNA Damage and Apoptosis Induced by Metabolites of Butylated Hydroxytoluene

Saeko Oikawa, Kohsuke Nishino, Shinji Oikawa, Sumiko Inoue, Tamio Mizutani, Shosuke Kawanishi

Journal:

Biochemical Pharmacology

Year:

1998

Language:

english

File:

PDF, 630 KB

english, 1998

16

Purification and Some Properties of Two Enzymes from Rat Liver Cytosol That Catalyze Carbonyl Reduction of 6-tert-Butyl-2,3-epoxy-5-cyclohexene-1,4-dione, a Metabolite of 3-tert-Butyl-4-hydroxyanisole

Kazuo Tajima, Mari Hashizaki, Kenji Yamamoto, Shizuo Narimatsu, Tamio Mizutani

Journal:

Archives of Biochemistry and Biophysics

Year:

1999

Language:

english

File:

PDF, 100 KB

english, 1999

17

Formation of a glutathione conjugate from butylated hydroxytoluene by rat liver microsomes

Kazuo Tajima, Kenji Yamamoto, Tamio Mizutani

Journal:

Biochemical Pharmacology

Year:

1985

Language:

english

File:

PDF, 632 KB

english, 1985

18

Bromo(methylthio)benzenes and related sulfur-containing compounds: Minor urinary metabolites of bromobenzene in rats

Tamio Mizutani, Kenji Yamamoto, Kazuo Tajima

Journal:

Biochemical and Biophysical Research Communications

Year:

1978

Language:

english

File:

PDF, 317 KB

english, 1978

19

Relative hepatotoxicity of 2-(substituted phenyl)thiazoles and substituted thiobenzamides in mice: evidence for the involvement of thiobenzamides as ring cleavage metabolites in the hepatotoxicity of 2-phenylthiazoles

Tamio Mizutani, Kiyomi Suzuki

Journal:

Toxicology Letters

Year:

1996

Language:

english

File:

PDF, 498 KB

english, 1996

20

Urinary nitrite in Japanese patients with urinary tract infections

Tamio Mizutani, Noriko Akinaga, Hiroshi Takatera

Journal:

Science of The Total Environment

Year:

1989

Language:

english

File:

PDF, 258 KB

english, 1989

21

Modulation of halobenzene-induced hepatotoxicity by DT-diaphorase modulators, butylated hydroxyanisole and dicoumarol: evidence for possible involvement of quinone metabolites in the toxicity of halobenzenes

Tamio Mizutani, Yoko Miyamoto

Journal:

Toxicology Letters

Year:

1999

Language:

english

File:

PDF, 71 KB

english, 1999

22

Pepleomycin-induced pneumonitis resulting in death

Watanabe, Izumi, Yokobayashi, Toshio, Nakajima, Tamio, Mizutani, Hidemori, Ohashi, Yasushi

Journal:

Journal of Maxillofacial Surgery

Year:

1984

Language:

english

File:

PDF, 2.09 MB

english, 1984

23

Physical and Psychical Factors in Disease.

Kawanishi, Shosuke, Mizutani, Tamio, Sano, Seiyo

Journal:

Year:

1922

Language:

english

File:

PDF, 185 KB

english, 1922

24

Induction of porphyrin synthesis in chick embryo liver cell culture by synthetic polychlorobiphenyl isomers

Kawanishi, Shosuke, Mizutani, Tamio, Sano, Seiyo

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1978

Language:

english

File:

PDF, 824 KB

english, 1978

25

The acute toxicity of butylated hydroxytoluene and its metabolites in mice

Kenji, Yamamoto, Kazuo, Tajima, Tamio, Mizutani

Journal:

Toxicology Letters

Year:

1980

Language:

english

File:

PDF, 216 KB

english, 1980

26

Modification of butylated hydroxytoluene-induced pulmonary toxicity in mice by diethyl maleate, buthionine sulfoximine, and cysteine

Mizutani, Tamio, Nomura, Haruko, Yamamoto, Kenji, Tajima, Kazuo

Journal:

Toxicology Letters

Year:

1984

Language:

english

File:

PDF, 304 KB

english, 1984

27

Evidence for the Involvement of N -Methylthiourea, a Ring Cleavage Metabolite, in the Hepatotoxicity of Methimazole in Glutathione-Depleted Mice: Structure−Toxicity and Metabolic Studies

Mizutani, Tamio, Yoshida, Kaoru, Murakami, Mihoko, Shirai, Mutsuko, Kawazoe, Sadahiro

Journal:

Chemical Research in Toxicology

Year:

2000

Language:

english

File:

PDF, 127 KB

english, 2000

28

Possible role of thioformamide as a proximate toxicant in the nephrotoxicity of thiabendazole and related thiazoles in glutathione-depleted mice: Structure-toxicity and metabolic studies

Mizutani, Tamio, Yoshida, Kaoru, Kawazoe, Sadahiro

Journal:

Chemical Research in Toxicology

Year:

1993

Language:

english

File:

PDF, 735 KB

english, 1993

29

The structure of the alkaloid protostemonine

Irie, Hiroshi, Harada, Hiroshi, Ohno, Kosei, Mizutani, Tamio, Uyeo, Shojiro

Journal:

Journal of the Chemical Society D Chemical Communications

Year:

1970

Language:

english

File:

PDF, 213 KB

english, 1970

30

An improved synthesis of (�)-lycoramine

Misaka, Yoshiharu, Mizutani, Tamio, Sekido, Mamoru, Uyeo, Shojiro

Journal:

Chemical Communications (London)

Year:

1967

Language:

english

File:

PDF, 156 KB

english, 1967

31

The total synthesis of (�)-lycoramine. Part I

Hazama, Naohiko, Irie, Hiroshi, Mizutani, Tamio, Shingu, Tetsuro, Takada, Masao, Uyeo, Shojiro, Yoshitake, Akira

Journal:

Journal of the Chemical Society C Organic

Year:

1968

Language:

english

File:

PDF, 984 KB

english, 1968

32

Adverse Response to Nifedipine in Unstable Angina Pectoris

Yokoyama, Mitsuhiro, Koizumi, Tamio, Fujitani, Kazuhiro, Mizutani, Tetsuo, Fukuzaki, Hisashi

Journal:

Year:

1982

Language:

english

File:

PDF, 617 KB

english, 1982

33

Electronic and Structural Requirements for Metabolic Activation of Butylated Hydroxytoluene Analogs to Their Quinone Methides, Intermediates Responsible for Lung Toxicity in Mice.

YAMAMOTO, Kenji, KATO, Sachiko, TAJIMA, Kazuo, MIZUTANI, Tamio

Journal:

Biological & Pharmaceutical Bulletin

Year:

1997

File:

PDF, 519 KB

1997

34

Identification of new metabolites of butylated hydroxytoluene (BHT) in rats.

YAMAMOTO, KENJI, TAJIMA, KAZUO, MIZUTANI, TAMIO

Journal:

Journal of Pharmacobio-Dynamics

Year:

1979

File:

PDF, 540 KB

1979

35

Sulfur-containing metabolites of 2,5,2',5'-tetrachlorobiphenyl, a major component of commercial PCB's.

MIO, TAKAYA, SUMINO, KIMIAKI, MIZUTANI, TAMIO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1976

File:

PDF, 430 KB

1976

36

Biotransformation of butylated hydroxytoluene (BHT) to BHT-quinone methide in rats.

TAJIMA, KAZUO, YAMAMOTO, KENJI, MIZUTANI, TAMIO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1981

File:

PDF, 530 KB

1981

37

Identification and determination of glutathione and glucuronide conjugates formed from butylated hydroxytoluene in rats.

TAJIMA, KAZUO, YAMAMOTO, KENJI, MIZUTANI, TAMIO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1983

File:

PDF, 688 KB

1983

38

Further metabolism of 3,5-di-tert-butyl-4-hydroxybenzoic acid, a major metabolite of butylated hydroxytoluene, in rats.

YAMAMOTO, Kenji, TAJIMA, Kazuo, TAKEMURA, Mari, MIZUTANI, Tamio

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1991

File:

PDF, 474 KB

1991

39

Synthesis of Nitrogen-containing Cyclic Compounds. CXXIV. Synthesis of Imidazopyridine Derivatives. (3)

Takahashi, Torizo, Kanematsu, Ken, Oh-ishi, Ryota, Mizutani, Tamio

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1960

File:

PDF, 635 KB

1960

40

Comparison of Susceptibility of Liver and Kidney to Lipid Peroxidation Induction by Cr(IV), Cr(V) and Cr(VI) Compounds

Hojo, Yasuji, Nishiguchi, Kiyoko, Kawazoe, Sadahiro, Mizutani, Tamio

Journal:

JOURNAL OF HEALTH SCIENCE

Year:

1999

File:

PDF, 614 KB

1999

41

Enhancement of Lipid Peroxidation by Chromium(IV) and Chromium(V) is Remarkable Compared to That by Chromium(VI) and is Effectively Suppressed by Scavengers of Reactive Oxygen Species

Hojo, Yasuji, Nishiguchi, Kiyoko, Kawazoe, Sadahiro, Mizutani, Tamio

Journal:

JOURNAL OF HEALTH SCIENCE

Year:

2000

File:

PDF, 827 KB

2000

42

Effect of Natural Food Colorants (Gardenia Color, Cochineal Extract) on the Hepatotoxicity of Chloroform in Mice(PROCEEDINGS OF 24TH SYMPOSIUM ON TOXICOLOGY AND ENVIRONMENTAL HEALTH)

Kawazoe, Sadahiro, Tanimoto, Yuki, Kurita, Fumie, Mizutani, Tamio

Journal:

JOURNAL OF HEALTH SCIENCE

Year:

1999

File:

PDF, 289 KB

1999

43

Separation and Determination of Polychlorinated Biphenyls and DDE by Oxidation in Solid Support

MIZUTANI, TAMIO, MATSUMOTO, MASAYOSHI

Journal:

Year:

1973

File:

PDF, 700 KB

1973

44

Hygienic Chemical Studies on 3, 5-Di-tert-butyl-4-hydroxytoluene (BHT). I. Microdetermination of 3, 5-Di-tert-butyl-4-hydroxytoluene (BHT) by Gas Chromatography

MIZUTANI, TAMIO, OHE, TAKESHI

Journal:

Year:

1976

File:

PDF, 581 KB

1976

45

Hepatotoxicity of Butylated Hydroxytoluene (BHT) in Glutathione-Depleted Mice (Proceedings of the 12 th Symposium on Environmental Pollutants and Toxicology) (Regular Presentations)

MIZUTANI, TAMIO, NOMURA, HARUKO, NAKANISHI, KAZUO, FUJITA, SETSUYA

Journal:

Year:

1986

File:

PDF, 270 KB

1986

46

Hygienic Chemical Studies on 3, 5-Di-tert-butyl-4-hydroxytoluene (BHT). II. Determination of 3, 5-Di-tert-butyl-4-hydroxytoluene (BHT) in Human Adipose Tissue

MIZUTANI, TAMIO, OHE, TAKESHI

Journal:

Year:

1976

File:

PDF, 651 KB

1976

47

Evaluation of Hepatotoxicity and Nephrotoxicity of Natural Food Colorants in Mice Depleted of Glutathione by DL-Buthionine Sulfoximine

Kawazoe, Sadahiro, Hojo, Yasuji, Mizutani, Tamio

Journal:

JOURNAL OF HEALTH SCIENCE

Year:

2000

File:

PDF, 467 KB

2000

48

Observation of Microexplosions in Spray Flames of Light Oil-Water Emulsions (2nd Report, Influence of Temporal and Spatial Resolution in High Speed Videography)

FUCHIHATA, Manabu, IDA, Tamio, MIZUTANI, Yukio

Journal:

TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series B

Year:

2003

File:

PDF, 1.08 MB

2003

49

Determination of Polychlorinated Biphenyls by Exhaustive Chlorination Method

MIZUTANI, Tamio, MATSUMOTO, Masayoshi

Journal:

Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi)

Year:

1972

Language:

english

File:

PDF, 1.04 MB

english, 1972

50

Studies on the Mutagenicity of Crude Drug Extracts. I

YAMAMOTO, HISAKO, MIZUTANI, TAMIO, NOMURA, HARUKO

Journal:

YAKUGAKU ZASSHI

Year:

1982

File:

PDF, 604 KB

1982